Homo sapiens Gene: C17orf70
Summary
InnateDB Gene IDBG-72343.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C17orf70
Gene Name chromosome 17 open reading frame 70
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185504
Encoded Proteins
chromosome 17 open reading frame 70
chromosome 17 open reading frame 70
chromosome 17 open reading frame 70
chromosome 17 open reading frame 70
chromosome 17 open reading frame 70
chromosome 17 open reading frame 70
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:81539885-81553961
Strand Reverse strand
Band q25.3
Transcripts
ENST00000327787 ENSP00000333283
ENST00000443656 ENSP00000395348
ENST00000425898 ENSP00000399674
ENST00000545865 ENSP00000459776
ENST00000541246 ENSP00000438149
ENST00000544302 ENSP00000444241
ENST00000536161 ENSP00000443415
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0043240 Fanconi anaemia nuclear complex
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Fanconi Anemia pathway pathway
DNA Repair pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.313905 Hs.548010
RefSeq NM_025161
HUGO
OMIM
CCDS CCDS32765
HPRD 07982
IMGT
EMBL
GenPept
RNA Seq Atlas