Homo sapiens Gene: ANAPC11
Summary
InnateDB Gene IDBG-72756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANAPC11
Gene Name anaphase promoting complex subunit 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141552
Encoded Proteins
anaphase promoting complex subunit 11
anaphase promoting complex subunit 11
anaphase promoting complex subunit 11
anaphase promoting complex subunit 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:81890790-81900991
Strand Forward strand
Band q25.3
Transcripts
ENST00000357385 ENSP00000349957
ENST00000344877 ENSP00000339695
ENST00000392376 ENSP00000376181
ENST00000571570 ENSP00000458143
ENST00000575195 ENSP00000458515
ENST00000577747 ENSP00000463567
ENST00000572639 ENSP00000460678
ENST00000583839 ENSP00000463598
ENST00000574924 ENSP00000460064
ENST00000584314 ENSP00000462250
ENST00000571874 ENSP00000459200
ENST00000572851 ENSP00000458265
ENST00000579978 ENSP00000463640
ENST00000578544 ENSP00000463357
ENST00000571024 ENSP00000461648
ENST00000585259 ENSP00000462527
ENST00000573956
ENST00000578550 ENSP00000464615
ENST00000582222 ENSP00000464403
ENST00000584197 ENSP00000464519
ENST00000577425 ENSP00000462691
ENST00000579133 ENSP00000463889
ENST00000612413 ENSP00000484031
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0007094 mitotic spindle assembly checkpoint
GO:0016567 protein ubiquitination
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070979 protein K11-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005680 anaphase-promoting complex
GO:0005730 nucleolus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Cellular responses to stress pathway
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase pathway
APC/C-mediated degradation of cell cycle proteins pathway
APC/C:Cdc20 mediated degradation of Cyclin B pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Regulation of mitotic cell cycle pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
APC/C:Cdc20 mediated degradation of Securin pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Autodegradation of Cdh1 by Cdh1:APC/C pathway
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
Adaptive Immune System pathway
Mitotic Spindle Checkpoint pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
M Phase pathway
Cellular Senescence pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Senescence-Associated Secretory Phenotype (SASP) pathway
Class I MHC mediated antigen processing & presentation pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Phosphorylation of the APC/C pathway
Cell Cycle Checkpoints pathway
Mitotic Metaphase and Anaphase pathway
KEGG
Cell cycle pathway
Oocyte meiosis pathway
Ubiquitin mediated proteolysis pathway
Progesterone-mediated oocyte maturation pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001002244 NM_001002245 NM_001002246 NM_001002247 NM_001002248 NM_001002249 NM_001289414 NM_001289415 NM_001289416 NM_001289417 NM_001289418 NM_001289419 NM_016476
HUGO
OMIM
CCDS CCDS11789 CCDS32769 CCDS74180
HPRD 12452
IMGT
EMBL
GenPept
RNA Seq Atlas