Homo sapiens Gene: GPD2 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-72772.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | GPD2 | ||||||||||||||||||
Gene Name | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | ||||||||||||||||||
Synonyms | GDH2; GPDM; mGPDH | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000115159 | ||||||||||||||||||
Encoded Proteins |
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 2:156435290-156613735 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q24.1 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
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KEGG |
Glycerophospholipid metabolism pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.148266 Hs.512382 Hs.618745 Hs.665979 Hs.735478 | ||||||||||||||||||
RefSeq | NM_000408 NM_001083112 XM_005246469 XM_005246470 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS2202 | ||||||||||||||||||
HPRD | 00715 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||