Version 5.4
Homo sapiens Gene: UPP2
Summary
InnateDB Gene IDBG-72986.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UPP2
Gene Name uridine phosphorylase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000007001
Encoded Proteins
IDBP-72988
uridine phosphorylase 2
IDBP-813367
uridine phosphorylase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:157876702-158136154
Strand Forward strand
Band q24.1
Transcripts
ENST00000005756 ENSP00000005756
ENST00000460456
ENST00000489438
ENST00000605860 ENSP00000474090
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
Biological Process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0009116 nucleoside metabolic process
GO:0009166 nucleotide catabolic process
GO:0043097 pyrimidine nucleoside salvage
GO:0044206 UMP salvage
GO:0044281 small molecule metabolic process
GO:0046108 uridine metabolic process
GO:0046135 pyrimidine nucleoside catabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0045098 type III intermediate filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026839
View Gene Order
ENSBTAG00000012801
Not yet available
Pathways
NETPATH
REACTOME
REACT_655
Pyrimidine salvage reactions pathway
REACT_1023
Pyrimidine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_957
Pyrimidine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00983
Drug metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.128427 Hs.602682
RefSeq NM_001135098 NM_173355
HUGO
OMIM
CCDS CCDS2207 CCDS46435
HPRD 15627
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca