Version 5.4
Homo sapiens Gene: MZF1
Summary
InnateDB Gene IDBG-73544.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MZF1
Gene Name myeloid zinc finger 1
Synonyms MZF-1; MZF1B; ZFP98; ZNF42; ZSCAN6
Species Homo sapiens
Ensembl Gene ENSG00000099326
Encoded Proteins
IDBP-73546
myeloid zinc finger 1
IDBP-763732
IDBP-764957
IDBP-766037
IDBP-761900
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:58561931-58573575
Strand Reverse strand
Band q13.43
Transcripts
ENST00000215057 ENSP00000215057
ENST00000596039 ENSP00000472454
ENST00000600048
ENST00000595245
ENST00000600004
ENST00000599369 ENSP00000469493
ENST00000594108 ENSP00000472123
ENST00000594234 ENSP00000469378
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030380
View Gene Order
ENSBTAG00000037581
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P28698
TrEMBL M0R2C0
UniProt Splice Variant
Entrez Gene 7593
UniGene Hs.399810
RefSeq NM_001267033 NM_003422 NM_198055 XM_005259203 XM_005259204 XM_006723359 XM_006723360
HUGO HGNC:13108
OMIM 194550
CCDS CCDS59427 CCDS12988
HPRD 01930
IMGT
EMBL AC016629 AC016630 AF055077 AF055078 AF161886 BC007777 BC053316 CH471135 M58297
GenPept AAA59898 AAD55809 AAD55810 AAF80465 AAF80466 AAH07777 AAH53316 EAW72617
RNA Seq Atlas 7593

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca