Homo sapiens Gene: KTN1
Summary
InnateDB Gene IDBG-7393.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KTN1
Gene Name kinectin 1 (kinesin receptor)
Synonyms CG1; KNT; MU-RMS-40.19;
Species Homo sapiens
Ensembl Gene ENSG00000126777
Encoded Proteins
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
kinectin 1 (kinesin receptor)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:55559072-55701526
Strand Forward strand
Band q22.3
Transcripts
ENST00000334975
ENST00000395314 ENSP00000378725
ENST00000395311 ENSP00000378722
ENST00000395309 ENSP00000378720
ENST00000395308 ENSP00000378719
ENST00000438792 ENSP00000391964
ENST00000413890 ENSP00000394992
ENST00000459737 ENSP00000432149
ENST00000557267 ENSP00000451641
ENST00000554567 ENSP00000452459
ENST00000555498 ENSP00000451878
ENST00000553360 ENSP00000452576
ENST00000554507 ENSP00000452073
ENST00000554890 ENSP00000452337
ENST00000555164
ENST00000554306
ENST00000554570 ENSP00000452205
ENST00000553624 ENSP00000452445
ENST00000555573 ENSP00000451698
ENST00000555172
ENST00000556631
ENST00000555506
ENST00000554294 ENSP00000451876
ENST00000554831
ENST00000553710 ENSP00000451139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019894 kinesin binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007018 microtubule-based movement
GO:0015031 protein transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
TNFalpha pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL G3V4Y7
UniProt Splice Variant
Entrez Gene 3895
UniGene Hs.509414 Hs.607216 Hs.653547
RefSeq NM_004986 NM_001079521 NM_001271014 NM_001079522 XM_006720138
HUGO HGNC:6467
OMIM 600381
CCDS CCDS41958 CCDS41957 CCDS41959
HPRD 02661
IMGT
EMBL AL138499 AL355773
GenPept
RNA Seq Atlas 3895