Homo sapiens Gene: ARCN1
Summary
InnateDB Gene IDBG-73982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARCN1
Gene Name archain 1
Synonyms COPD;
Species Homo sapiens
Ensembl Gene ENSG00000095139
Encoded Proteins
archain 1
archain 1
archain 1
archain 1
archain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118572390-118603033
Strand Forward strand
Band q23.3
Transcripts
ENST00000264028 ENSP00000264028
ENST00000359415 ENSP00000352385
ENST00000392859 ENSP00000376599
ENST00000534182 ENSP00000431676
ENST00000614498 ENSP00000482114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 35 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0008344 adult locomotory behavior
GO:0016192 vesicle-mediated transport
GO:0021691 cerebellar Purkinje cell layer maturation
GO:0043473 pigmentation
GO:0048193 Golgi vesicle transport
GO:0048205 COPI coating of Golgi vesicle
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0030126 COPI vesicle coat
GO:0030131 clathrin adaptor complex
GO:0030137 COPI-coated vesicle
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
COPI Mediated Transport pathway
Golgi to ER Retrograde Transport pathway
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.33642
RefSeq NM_001142281 NM_001655
HUGO
OMIM
CCDS CCDS44749 CCDS8400
HPRD 02893
IMGT
EMBL
GenPept
RNA Seq Atlas