Version 5.4
Homo sapiens Gene: ARCN1
Summary
InnateDB Gene IDBG-73982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARCN1
Gene Name archain 1
Synonyms COPD
Species Homo sapiens
Ensembl Gene ENSG00000095139
Encoded Proteins
IDBP-73984
archain 1
IDBP-73986
archain 1
IDBP-244802
archain 1
IDBP-590225
archain 1
IDBP-808821
archain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118572390-118603033
Strand Forward strand
Band q23.3
Transcripts
ENST00000264028 ENSP00000264028
ENST00000359415 ENSP00000352385
ENST00000392859 ENSP00000376599
ENST00000534182 ENSP00000431676
ENST00000614498 ENSP00000482114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 35 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0008344 adult locomotory behavior
GO:0016192 vesicle-mediated transport
GO:0021691 cerebellar Purkinje cell layer maturation
GO:0043473 pigmentation
GO:0048193 Golgi vesicle transport
GO:0048205 COPI coating of Golgi vesicle
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
GO:0030126 COPI vesicle coat
GO:0030131 clathrin adaptor complex
GO:0030137 COPI-coated vesicle
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032096
View Gene Order
ENSBTAG00000006690
Not yet available
Pathways
NETPATH
REACTOME
REACT_11096
COPI Mediated Transport pathway
REACT_11208
Golgi to ER Retrograde Transport pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.33642
RefSeq NM_001142281 NM_001655
HUGO
OMIM
CCDS CCDS44749 CCDS8400
HPRD 02893
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca