Version 5.4
Homo sapiens Gene: STARD8
Summary
InnateDB Gene IDBG-74012.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STARD8
Gene Name StAR-related lipid transfer (START) domain containing 8
Synonyms ARHGAP38; DLC3; STARTGAP3
Species Homo sapiens
Ensembl Gene ENSG00000130052
Encoded Proteins
IDBP-74014
StAR-related lipid transfer (START) domain containing 8
IDBP-74016
StAR-related lipid transfer (START) domain containing 8
IDBP-74018
StAR-related lipid transfer (START) domain containing 8
IDBP-482954
StAR-related lipid transfer (START) domain containing 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:68647666-68725842
Strand Forward strand
Band q13.1
Transcripts
ENST00000252336 ENSP00000252336
ENST00000374599 ENSP00000363727
ENST00000374597 ENSP00000363725
ENST00000488088
ENST00000523864 ENSP00000428031
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0008289 lipid binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0005925 focal adhesion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031216
View Gene Order
ENSBTAG00000033702
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.95140
RefSeq NM_001142503 NM_001142504 NM_014725 XM_005262314 XM_005262315
HUGO
OMIM
CCDS CCDS14390 CCDS48134
HPRD 06730
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca