Version 5.4
Homo sapiens Gene: CERS6
Summary
InnateDB Gene IDBG-74302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERS6
Gene Name ceramide synthase 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172292
Encoded Proteins
IDBP-74304
ceramide synthase 6
IDBP-245153
ceramide synthase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:168455862-168775137
Strand Forward strand
Band q24.3
Transcripts
ENST00000305747 ENSP00000306579
ENST00000392687 ENSP00000376453
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006665 sphingolipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027035
View Gene Order
ENSBTAG00000044179
Not yet available
Pathways
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q6ZMG9
TrEMBL
UniProt Splice Variant
Entrez Gene 253782
UniGene Hs.604034 Hs.743222
RefSeq NM_203463 NM_001256126 XM_005246440
HUGO HGNC:23826
OMIM 615336
CCDS CCDS2228 CCDS58734
HPRD 17258
IMGT
EMBL AC009475 AC019086 AC097453 AK172775 BC030800 BC109284 BC109285
GenPept AAH30800 AAI09285 AAI09286 BAD18757
RNA Seq Atlas 253782

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca