Version 5.4
Homo sapiens Protein: CERS6
Summary
InnateDB Protein IDBP-245153.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERS6
Protein Name ceramide synthase 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000376453
InnateDB Gene IDBG-74302 (CERS6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006665 sphingolipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR006634 TRAM/LAG1/CLN8 homology domain
IPR009057 Homeodomain-like
IPR016439 Longevity assurance, LAG1/LAC1
PFAM PF00046
PF03798
PRINTS
PIRSF PIRSF005225
SMART SM00389
SM00724
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZMG9
PhosphoSite PhosphoSite-Q6ZMG9
TrEMBL
UniProt Splice Variant
Entrez Gene 253782
UniGene Hs.743222
RefSeq NP_001243055
HUGO HGNC:23826
OMIM 615336
CCDS CCDS58734
HPRD 17258
IMGT
EMBL AC009475 AC019086 AC097453 AK172775 BC030800 BC109284 BC109285
GenPept AAH30800 AAI09285 AAI09286 BAD18757

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca