Homo sapiens Gene: CCDC6
Summary
InnateDB Gene IDBG-75157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCDC6
Gene Name coiled-coil domain containing 6
Synonyms D10S170; H4; PTC; TPC; TST1;
Species Homo sapiens
Ensembl Gene ENSG00000108091
Encoded Proteins
coiled-coil domain containing 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:59788763-59906656
Strand Reverse strand
Band q21.2
Transcripts
ENST00000263102 ENSP00000263102
ENST00000491922
ENST00000518638
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 29 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Pathways in cancer pathway
Thyroid cancer pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.327068 Hs.591360
RefSeq NM_005436
HUGO
OMIM
CCDS CCDS7257
HPRD 09064
IMGT
EMBL
GenPept
RNA Seq Atlas