Version 5.4
Homo sapiens Gene: ZMYM3
Summary
InnateDB Gene IDBG-75385.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZMYM3
Gene Name zinc finger, MYM-type 3
Synonyms DXS6673E; MYM; XFIM; ZNF198L2; ZNF261
Species Homo sapiens
Ensembl Gene ENSG00000147130
Encoded Proteins
IDBP-75387
zinc finger, MYM-type 3
IDBP-75391
zinc finger, MYM-type 3
IDBP-75393
zinc finger, MYM-type 3
IDBP-75395
zinc finger, MYM-type 3
IDBP-75397
zinc finger, MYM-type 3
IDBP-75399
zinc finger, MYM-type 3
IDBP-75401
zinc finger, MYM-type 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:71239624-71255146
Strand Reverse strand
Band q13.1
Transcripts
ENST00000373998 ENSP00000363110
ENST00000314425 ENSP00000322845
ENST00000373988 ENSP00000363100
ENST00000373984 ENSP00000363096
ENST00000373982 ENSP00000363094
ENST00000373981 ENSP00000363093
ENST00000373978 ENSP00000363090
ENST00000489332
ENST00000470832
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007275 multicellular organismal development
GO:0022604 regulation of cell morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031310
View Gene Order
ENSBTAG00000008492
Not yet available
Cross-References
SwissProt
TrEMBL A6NHB5
UniProt Splice Variant
Entrez Gene 9203
UniGene Hs.522684
RefSeq NM_001171162 NM_001171163 NM_005096 NM_201599 XM_005262309 XM_005262310 XM_006724715
HUGO HGNC:13054
OMIM 300061
CCDS CCDS14409 CCDS55443 CCDS55444
HPRD 02088
IMGT
EMBL AL590762
GenPept
RNA Seq Atlas 9203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca