Homo sapiens Gene: PUS3
Summary
InnateDB Gene IDBG-75686.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PUS3
Gene Name pseudouridylate synthase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000110060
Encoded Proteins
pseudouridylate synthase 3
pseudouridylate synthase 3
pseudouridylate synthase 3
pseudouridylate synthase 3
pseudouridylate synthase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:125893485-125903221
Strand Reverse strand
Band q24.2
Transcripts
ENST00000227474 ENSP00000227474
ENST00000530811 ENSP00000432386
ENST00000534158 ENSP00000432272
ENST00000529801 ENSP00000437077
ENST00000613398 ENSP00000481536
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
GO:0031119 tRNA pseudouridine synthesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9BZE2
TrEMBL E9PNY6 E9PRI9
UniProt Splice Variant
Entrez Gene 83480
UniGene Hs.660922
RefSeq NM_001271985 NM_031307 XM_005271687 XM_005271688
HUGO HGNC:25461
OMIM
CCDS CCDS73411 CCDS8466
HPRD
IMGT
EMBL AF325689 AK055702 AK314251 AP000842 BC004822 BC013427
GenPept AAG50280 AAH04822 AAH13427 BAB70990 BAG36917
RNA Seq Atlas 83480