Version 5.4
Homo sapiens Gene: GNL1
Summary
InnateDB Gene IDBG-76084.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNL1
Gene Name guanine nucleotide binding protein-like 1
Synonyms HSR1
Species Homo sapiens
Ensembl Gene ENSG00000204590
Encoded Proteins
IDBP-76086
guanine nucleotide binding protein-like 1
IDBP-368712
guanine nucleotide binding protein-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30541377-30557174
Strand Reverse strand
Band p21.33
Transcripts
ENST00000376621 ENSP00000365806
ENST00000433809 ENSP00000404728
ENST00000462708
ENST00000464231
ENST00000487166
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 10 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005525 GTP binding
Biological Process
GO:0002456 T cell mediated immunity
GO:0006184 GTP catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007165 signal transduction
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024429
View Gene Order
ENSBTAG00000025516
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.673997 Hs.83147
RefSeq NM_005275 XM_005249015 XM_005275093 XM_005275235
HUGO
OMIM
CCDS CCDS4680
HPRD 00879
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca