Version 5.4
Homo sapiens Gene: AATF
Summary
InnateDB Gene IDBG-775904.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AATF
Gene Name apoptosis antagonizing transcription factor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000275700
Encoded Proteins
IDBP-811071
apoptosis antagonizing transcription factor
IDBP-811074
apoptosis antagonizing transcription factor
IDBP-811075
apoptosis antagonizing transcription factor
IDBP-811076
apoptosis antagonizing transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:36948875-37056871
Strand Forward strand
Band q12
Transcripts
ENST00000619387 ENSP00000477848
ENST00000613840 ENSP00000479926
ENST00000610798 ENSP00000480472
ENST00000616434 ENSP00000477881
ENST00000616392
ENST00000617141
ENST00000622432
ENST00000616062
ENST00000615319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
Experimentally validated
Total 52 [view]
Protein-Protein 49 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0043522 leucine zipper domain binding
GO:0044822 poly(A) RNA binding
GO:0048156 tau protein binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0007155 cell adhesion
GO:0007346 regulation of mitotic cell cycle
GO:0032929 negative regulation of superoxide anion generation
GO:0040016 embryonic cleavage
GO:0042254 ribosome biogenesis
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0097190 apoptotic signaling pathway
GO:2000378 negative regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005925 focal adhesion
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_012138
HUGO
OMIM
CCDS CCDS32632
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca