InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AATF

Summary

InnateDB Protein

IDBP-811071.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AATF

Protein Name

apoptosis antagonizing transcription factor

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000477848

InnateDB Gene

IDBG-775904 (AATF)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0043522	leucine zipper domain binding
GO:0044822	poly(A) RNA binding
GO:0048156	tau protein binding

Biological Process

GO:0006974	cellular response to DNA damage stimulus
GO:0007155	cell adhesion
GO:0007346	regulation of mitotic cell cycle
GO:0032929	negative regulation of superoxide anion generation
GO:0040016	embryonic cleavage
GO:0042254	ribosome biogenesis
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0097190	apoptotic signaling pathway
GO:2000378	negative regulation of reactive oxygen species metabolic process