Homo sapiens Gene: SPOCK2
Summary
InnateDB Gene IDBG-77813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPOCK2
Gene Name sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
Synonyms testican-2;
Species Homo sapiens
Ensembl Gene ENSG00000107742
Encoded Proteins
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:72059035-72089032
Strand Reverse strand
Band q22.1
Transcripts
ENST00000317376 ENSP00000321108
ENST00000373109 ENSP00000362201
ENST00000412663 ENSP00000397715
ENST00000463279
ENST00000469121
ENST00000460053
ENST00000495888
ENST00000483699
ENST00000536168 ENSP00000439445
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005539 glycosaminoglycan binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0007165 signal transduction
GO:0007416 synapse assembly
GO:0010811 positive regulation of cell-substrate adhesion
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0030198 extracellular matrix organization
GO:0045595 regulation of cell differentiation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q92563
TrEMBL B4DFA9
UniProt Splice Variant
Entrez Gene 9806
UniGene Hs.523009 Hs.623618
RefSeq NM_014767 NM_001134434 NM_001244950 XM_005270302
HUGO HGNC:13564
OMIM 607988
CCDS CCDS7313 CCDS44431
HPRD 12146
IMGT
EMBL AC022392 AJ001453 AK294008 AK307091 AY358921 BC023558 D87465
GenPept AAH23558 AAQ89280 BAA13404 BAG57370 CAA04774
RNA Seq Atlas 9806