Homo sapiens Gene: GTF3C3
Summary
InnateDB Gene IDBG-77823.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF3C3
Gene Name general transcription factor IIIC, polypeptide 3, 102kDa
Synonyms TFIIIC102; TFiiiC2-102; TFIIICgamma;
Species Homo sapiens
Ensembl Gene ENSG00000119041
Encoded Proteins
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
general transcription factor IIIC, polypeptide 3, 102kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:196763032-196799725
Strand Reverse strand
Band q33.1
Transcripts
ENST00000263956 ENSP00000263956
ENST00000409364 ENSP00000386465
ENST00000416690 ENSP00000391724
ENST00000435252 ENSP00000394065
ENST00000448087 ENSP00000398385
ENST00000455546 ENSP00000389992
ENST00000448539 ENSP00000406685
ENST00000451088 ENSP00000438797
ENST00000481098
ENST00000466862
ENST00000470386
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0010467 gene expression
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0042797 tRNA transcription from RNA polymerase III promoter
Cellular Component
GO:0000127 transcription factor TFIIIC complex
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
KEGG
INOH
PID BIOCARTA
Rna polymerase iii transcription [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.470996 Hs.603453 Hs.737375
RefSeq NM_001206774 NM_012086 XM_005246965
HUGO
OMIM
CCDS CCDS2316 CCDS56153
HPRD 11997
IMGT
EMBL
GenPept
RNA Seq Atlas