Version 5.4
Homo sapiens Gene: ZNF335
Summary
InnateDB Gene IDBG-78666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF335
Gene Name zinc finger protein 335
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198026
Encoded Proteins
IDBP-78668
zinc finger protein 335
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:45948653-45972172
Strand Reverse strand
Band q13.12
Transcripts
ENST00000322927 ENSP00000325326
ENST00000475002
ENST00000476822
ENST00000494955
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001701 in utero embryonic development
GO:0002052 positive regulation of neuroblast proliferation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007420 brain development
GO:0010468 regulation of gene expression
GO:0021895 cerebral cortex neuron differentiation
GO:0040029 regulation of gene expression, epigenetic
GO:0048812 neuron projection morphogenesis
GO:0048854 brain morphogenesis
GO:0050671 positive regulation of lymphocyte proliferation
GO:0050767 regulation of neurogenesis
GO:0050769 positive regulation of neurogenesis
GO:0051569 regulation of histone H3-K4 methylation
GO:0080182 histone H3-K4 trimethylation
Cellular Component
GO:0005634 nucleus
GO:0035097 histone methyltransferase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039834
View Gene Order
ENSBTAG00000010130
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.174193
RefSeq NM_022095 XM_005260504 XM_005260506
HUGO
OMIM
CCDS CCDS13389
HPRD 11709
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca