Homo sapiens Gene: CAMK2G | |||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||
InnateDB Gene | IDBG-78703.6 | ||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||
Gene Symbol | CAMK2G | ||||||||||||||||||||||||||||
Gene Name | calcium/calmodulin-dependent protein kinase II gamma | ||||||||||||||||||||||||||||
Synonyms | CAMK; CAMK-II; CAMKG | ||||||||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||||||||
Ensembl Gene | ENSG00000148660 | ||||||||||||||||||||||||||||
Encoded Proteins |
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
calcium/calmodulin-dependent protein kinase II gamma
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Protein Structure | |||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
Summary |
The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011] |
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Gene Information | |||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||
Genomic Location | Chromosome 10:73812501-73874591 | ||||||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||||||
Band | q22.2 | ||||||||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||||||||
Interactions | |||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||
Species
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||||||||
NETPATH |
TGF_beta_Receptor pathway
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REACTOME |
Interferon gamma signaling pathway
Ras activation uopn Ca2+ infux through NMDA receptor pathway
CREB phosphorylation through the activation of Ras pathway
CREB phosphorylation through the activation of CaMKII pathway
Unblocking of NMDA receptor, glutamate binding and activation pathway
Trafficking of AMPA receptors pathway
Cellular responses to stress pathway
Neuronal System pathway
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Post NMDA receptor activation events pathway
Immune System pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
HSF1-dependent transactivation pathway
Cellular response to heat stress pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
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KEGG |
GnRH signaling pathway pathway
Wnt signaling pathway pathway
Olfactory transduction pathway
ErbB signaling pathway pathway
Long-term potentiation pathway
Glioma pathway
Calcium signaling pathway pathway
Melanogenesis pathway
Neurotrophin signaling pathway pathway
Oocyte meiosis pathway
Gastric acid secretion pathway
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INOH |
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
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PID NCI |
BCR signaling pathway
N-cadherin signaling events
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Cross-References | |||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||
TrEMBL | Q8WU40 | ||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||
Entrez Gene | 818 | ||||||||||||||||||||||||||||
UniGene | Hs.717383 Hs.730922 | ||||||||||||||||||||||||||||
RefSeq | NM_001204492 NM_001222 NM_172169 NM_172170 NM_172171 NM_172173 | ||||||||||||||||||||||||||||
HUGO | HGNC:1463 | ||||||||||||||||||||||||||||
OMIM | 602123 | ||||||||||||||||||||||||||||
CCDS | CCDS73153 CCDS7336 CCDS7337 CCDS7338 | ||||||||||||||||||||||||||||
HPRD | 03672 | ||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||
EMBL | AC022400 AL596247 AL713896 BC021269 | ||||||||||||||||||||||||||||
GenPept | AAH21269 | ||||||||||||||||||||||||||||
RNA Seq Atlas | 818 | ||||||||||||||||||||||||||||