Version 5.4
| Homo sapiens Gene: SLC13A3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-79300.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SLC13A3 | ||||||||
| Gene Name | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000158296 | ||||||||
| Encoded Proteins |
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 20:46557823-46684467 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | q13.12 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Sodium-coupled sulphate, di- and tri-carboxylate transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Hs.602163 Hs.655498 Hs.670365 | ||||||||
| RefSeq | NM_001011554 NM_001193339 NM_001193340 NM_001193342 NM_022829 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | CCDS13400 CCDS42886 CCDS54469 CCDS54470 | ||||||||
| HPRD | 10450 | ||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||