InnateDB Protein
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IDBP-79306.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC13A3
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Protein Name
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solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000361193
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InnateDB Gene
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IDBG-79300 (SLC13A3)
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Protein Structure
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Function |
High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:17426067}; Multi-pass membrane protein {ECO:0000269PubMed:17426067}.
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Disease Associations |
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Tissue Specificity |
Expression is highest in kidney. Detected in placenta, brain, liver and pancreas.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001898
Sodium/sulphate symporter
IPR004680
Citrate transporter-like domain
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PFAM |
PF00939
PF03600
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8WWT9
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PhosphoSite |
PhosphoSite-Q8WWT9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
64849
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UniGene |
Hs.670365
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RefSeq |
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HUGO |
HGNC:14430
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OMIM |
606411
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CCDS |
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HPRD |
10450
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IMGT |
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EMBL |
AF154121
AK056713
AK096658
AK295748
AL034424
AL133520
AL442082
AY072810
BC035966
CH471077
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GenPept |
AAF73251
AAH35966
AAL66762
BAB71262
BAC04834
BAG58580
CAC09447
EAW75725
EAW75726
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