Version 5.4
Homo sapiens Gene: SPAG16
Summary
InnateDB Gene IDBG-80075.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPAG16
Gene Name sperm associated antigen 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144451
Encoded Proteins
IDBP-80077
sperm associated antigen 16
IDBP-80083
sperm associated antigen 16
IDBP-293084
sperm associated antigen 16
IDBP-388740
sperm associated antigen 16
IDBP-388741
sperm associated antigen 16
IDBP-388742
sperm associated antigen 16
IDBP-388743
sperm associated antigen 16
IDBP-388744
sperm associated antigen 16
IDBP-388748
sperm associated antigen 16
IDBP-388750
sperm associated antigen 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:213284379-214410501
Strand Forward strand
Band q34
Transcripts
ENST00000272898 ENSP00000272898
ENST00000331683 ENSP00000332592
ENST00000406979 ENSP00000385496
ENST00000432529 ENSP00000415079
ENST00000413312 ENSP00000390494
ENST00000440779 ENSP00000404949
ENST00000420497 ENSP00000411077
ENST00000452556 ENSP00000398926
ENST00000447990 ENSP00000400847
ENST00000414961
ENST00000451561 ENSP00000416600
ENST00000480494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0007283 spermatogenesis
GO:0042384 cilium assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005930 axoneme
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000053153
View Gene Order
ENSBTAG00000018549
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.743365
RefSeq NM_001025436 NM_024532 XM_006712744 XM_006712746 XM_006712747
HUGO
OMIM
CCDS CCDS2396 CCDS46508
HPRD 18089
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca