Homo sapiens Gene: RHBDL1
Summary
InnateDB Gene IDBG-8019.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHBDL1
Gene Name rhomboid, veinlet-like 1 (Drosophila)
Synonyms RHBDL; RRP;
Species Homo sapiens
Ensembl Gene ENSG00000103269
Encoded Proteins
rhomboid, veinlet-like 1 (Drosophila)
rhomboid, veinlet-like 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:675666-678268
Strand Forward strand
Band p13.3
Transcripts
ENST00000352681 ENSP00000344206
ENST00000219551 ENSP00000219551
ENST00000450775
ENST00000561556 ENSP00000455608
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.137572
RefSeq NM_001278720 NM_001278721 XM_005255666
HUGO
OMIM
CCDS CCDS61779
HPRD 07050
IMGT
EMBL
GenPept
RNA Seq Atlas