Version 5.4
Homo sapiens Gene: TMBIM1
Summary
InnateDB Gene IDBG-80943.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMBIM1
Gene Name transmembrane BAX inhibitor motif containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135926
Encoded Proteins
IDBP-80945
transmembrane BAX inhibitor motif containing 1
IDBP-236720
transmembrane BAX inhibitor motif containing 1
IDBP-388882
transmembrane BAX inhibitor motif containing 1
IDBP-388883
transmembrane BAX inhibitor motif containing 1
IDBP-388884
transmembrane BAX inhibitor motif containing 1
IDBP-388885
transmembrane BAX inhibitor motif containing 1
IDBP-388886
transmembrane BAX inhibitor motif containing 1
IDBP-388887
transmembrane BAX inhibitor motif containing 1
IDBP-388888
transmembrane BAX inhibitor motif containing 1
IDBP-388889
transmembrane BAX inhibitor motif containing 1
IDBP-388890
transmembrane BAX inhibitor motif containing 1
IDBP-388891
transmembrane BAX inhibitor motif containing 1
IDBP-388892
transmembrane BAX inhibitor motif containing 1
IDBP-388893
transmembrane BAX inhibitor motif containing 1
IDBP-388894
transmembrane BAX inhibitor motif containing 1
IDBP-388895
transmembrane BAX inhibitor motif containing 1
IDBP-388896
transmembrane BAX inhibitor motif containing 1
IDBP-388897
transmembrane BAX inhibitor motif containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:218274192-218292586
Strand Reverse strand
Band q35
Transcripts
ENST00000258412 ENSP00000258412
ENST00000396809 ENSP00000380025
ENST00000444881 ENSP00000409738
ENST00000437694 ENSP00000404709
ENST00000445635 ENSP00000401491
ENST00000439306 ENSP00000414572
ENST00000429501 ENSP00000399987
ENST00000425694 ENSP00000399345
ENST00000418569 ENSP00000406744
ENST00000440422 ENSP00000412518
ENST00000444183 ENSP00000410136
ENST00000453776 ENSP00000410771
ENST00000444000 ENSP00000403462
ENST00000453281 ENSP00000395614
ENST00000451181 ENSP00000394946
ENST00000434015 ENSP00000405516
ENST00000413976 ENSP00000408729
ENST00000420341 ENSP00000413624
ENST00000465082
ENST00000492966
ENST00000466012
ENST00000476429
ENST00000495113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005123 death receptor binding
Biological Process
GO:0048553 negative regulation of metalloenzyme activity
GO:0090005 negative regulation of establishment of protein localization to plasma membrane
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902045 negative regulation of Fas signaling pathway
GO:2000504 positive regulation of blood vessel remodeling
Cellular Component
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006301
View Gene Order
ENSBTAG00000003935
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591605
RefSeq NM_022152 XM_005246758 XM_005246761 XM_005246762
HUGO
OMIM
CCDS CCDS2412
HPRD 17884
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca