Version 5.4
Homo sapiens Gene: NRK
Summary
InnateDB Gene IDBG-81057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NRK
Gene Name Nik related kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000123572
Encoded Proteins
IDBP-591508
Nik related kinase
IDBP-595866
Nik related kinase
IDBP-603587
Nik related kinase
IDBP-595229
Nik related kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:105822543-105958610
Strand Forward strand
Band q22.3
Transcripts
ENST00000243300 ENSP00000434830
ENST00000428173 ENSP00000438378
ENST00000536164 ENSP00000438785
ENST00000540278 ENSP00000438148
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005083 small GTPase regulator activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007256 activation of JNKK activity
GO:0007567 parturition
GO:0008285 negative regulation of cell proliferation
GO:0016310 phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0050790 regulation of catalytic activity
GO:0060721 regulation of spongiotrophoblast cell proliferation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052854
View Gene Order
ENSBTAG00000004836
Not yet available
Cross-References
SwissProt Q7Z2Y5
TrEMBL B7Z1I7 B7Z6I7 F5H049
UniProt Splice Variant
Entrez Gene 203447
UniGene Hs.209527 Hs.695203 Hs.739153
RefSeq NM_198465 XM_006724631
HUGO HGNC:25391
OMIM 300791
CCDS CCDS65305
HPRD
IMGT
EMBL AK131549 AK293500 AK300377 BC108702 BX538345 Z68339 Z69734 Z70274 Z83850 Z97356
GenPept AAI08703 BAD18683 BAH11523 BAH13273 CAD98108
RNA Seq Atlas 203447

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca