Homo sapiens Protein: NRK
Summary
InnateDB Protein IDBP-603587.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NRK
Protein Name Nik related kinase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000438785
InnateDB Gene IDBG-81057 (NRK)
Protein Structure
UniProt Annotation
Function May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005083 small GTPase regulator activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0023014 signal transduction by phosphorylation
GO:0050790 regulation of catalytic activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00069
PF07714
PRINTS PR00109
PIRSF
SMART SM00220
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z2Y5
PhosphoSite PhosphoSite-Q7Z2Y5
TrEMBL
UniProt Splice Variant
Entrez Gene 203447
UniGene Hs.739153
RefSeq
HUGO HGNC:25391
OMIM 300791
CCDS
HPRD 14841
IMGT
EMBL AK131549 BC108702 BX538345 Z68339 Z69734 Z70274 Z83850
GenPept AAI08703 BAD18683 CAD98108