Version 5.4
Homo sapiens Gene: PTBP3
Summary
InnateDB Gene IDBG-81247.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTBP3
Gene Name polypyrimidine tract binding protein 3
Synonyms ROD1
Species Homo sapiens
Ensembl Gene ENSG00000119314
Encoded Proteins
IDBP-81249
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-81251
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-81253
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-81255
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-81257
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-377996
ROD1 regulator of differentiation 1 (S. pombe)
IDBP-378014
ROD1 regulator of differentiation 1 (S. pombe)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:112217716-112333667
Strand Reverse strand
Band q32
Transcripts
ENST00000374257 ENSP00000363375
ENST00000374255 ENSP00000363373
ENST00000334318 ENSP00000334499
ENST00000343327 ENSP00000340705
ENST00000210227 ENSP00000210227
ENST00000458258 ENSP00000414921
ENST00000450374 ENSP00000388024
ENST00000487997
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0009653 anatomical structure morphogenesis
GO:0033119 negative regulation of RNA splicing
GO:0043249 erythrocyte maturation
GO:0045595 regulation of cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028382
View Gene Order
ENSBTAG00000016750
Not yet available
Cross-References
SwissProt O95758
TrEMBL
UniProt Splice Variant
Entrez Gene 9991
UniGene Hs.269988 Hs.610013 Hs.621703
RefSeq NM_001163788 NM_001244897 XM_005252324 XM_006717345 XM_006717346 NM_001163790 NM_001244896 NM_001244898 NM_005156 XM_006717343 XM_006717344
HUGO HGNC:10253
OMIM 607527
CCDS CCDS55332 CCDS55333 CCDS59140 CCDS59141 CCDS6784
HPRD 09603
IMGT
EMBL AB023967 AK001685 AK302558 AL158824 AL359073 BC039896 BC044585 BI463123 CH471105 CR749471
GenPept AAH39896 AAH44585 BAA75466 BAG50959 BAG63824 CAH18301 CAI12349 CAI12350 CAI12353 CAI12354 CAI14112 CAI14113 EAW59100
RNA Seq Atlas 9991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca