Homo sapiens Gene: SLC31A1
Summary
InnateDB Gene IDBG-81536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC31A1
Gene Name solute carrier family 31 (copper transporters), member 1
Synonyms COPT1; CTR1;
Species Homo sapiens
Ensembl Gene ENSG00000136868
Encoded Proteins
solute carrier family 31 (copper transporters), member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:113221562-113264492
Strand Forward strand
Band q32
Transcripts
ENST00000374212 ENSP00000363329
ENST00000496650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 2 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005375 copper ion transmembrane transporter activity
GO:0005515 protein binding
GO:0015088 copper uptake transmembrane transporter activity
Biological Process
GO:0006825 copper ion transport
GO:0006855 drug transmembrane transport
GO:0006878 cellular copper ion homeostasis
GO:0015677 copper ion import
GO:0035434 copper ion transmembrane transport
GO:0055085 transmembrane transport
GO:0072719 cellular response to cisplatin
GO:1902861 copper ion import into cell
Cellular Component
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Metal ion SLC transporters pathway
SLC-mediated transmembrane transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.532315 Hs.661363
RefSeq NM_001859
HUGO
OMIM
CCDS CCDS6789
HPRD 04362
IMGT
EMBL
GenPept
RNA Seq Atlas