Version 5.4
Homo sapiens Gene: SLC31A1
Summary
InnateDB Gene IDBG-81536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC31A1
Gene Name solute carrier family 31 (copper transporters), member 1
Synonyms COPT1; CTR1
Species Homo sapiens
Ensembl Gene ENSG00000136868
Encoded Proteins
IDBP-81538
solute carrier family 31 (copper transporters), member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:113221562-113264492
Strand Forward strand
Band q32
Transcripts
ENST00000374212 ENSP00000363329
ENST00000496650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 2 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005375 copper ion transmembrane transporter activity
GO:0005515 protein binding
GO:0015088 copper uptake transmembrane transporter activity
Biological Process
GO:0006825 copper ion transport
GO:0006855 drug transmembrane transport
GO:0006878 cellular copper ion homeostasis
GO:0015677 copper ion import
GO:0035434 copper ion transmembrane transport
GO:0055085 transmembrane transport
GO:0072719 cellular response to cisplatin
GO:1902861 copper ion import into cell
Cellular Component
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000066150
View Gene Order
ENSBTAG00000021678
Not yet available
Pathways
NETPATH
REACTOME
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.532315 Hs.661363
RefSeq NM_001859
HUGO
OMIM
CCDS CCDS6789
HPRD 04362
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca