Version 5.4
Homo sapiens Gene: COL27A1
Summary
InnateDB Gene IDBG-82019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COL27A1
Gene Name collagen, type XXVII, alpha 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196739
Encoded Proteins
IDBP-82021
collagen, type XXVII, alpha 1
IDBP-378447
collagen, type XXVII, alpha 1
IDBP-596177
collagen, type XXVII, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Fibrillar collagens, such as COL27A1, compose one of the most ancient families of extracellular matrix molecules. They form major structural elements in extracellular matrices of cartilage, skin, and tendon (Boot-Handford et al., 2003 [PubMed 12766169]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:114155560-114312511
Strand Forward strand
Band q32
Transcripts
ENST00000356083 ENSP00000348385
ENST00000451716 ENSP00000391328
ENST00000494090 ENSP00000432928
ENST00000485397
ENST00000477421
ENST00000494780
ENST00000490831
ENST00000468565
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0046872 metal ion binding
Biological Process
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005583 fibrillar collagen trimer
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045672
View Gene Order
ENSBTAG00000019807
Not yet available
Pathways
NETPATH
REACTOME
REACT_150180
Assembly of collagen fibrils and other multimeric structures pathway
REACT_121139
Collagen biosynthesis and modifying enzymes pathway
REACT_118779
Extracellular matrix organization pathway
REACT_120729
Collagen formation pathway
KEGG
hsa04512
ECM-receptor interaction pathway
hsa04510
Focal adhesion pathway
hsa05146
Amoebiasis pathway
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.494892 Hs.593318 Hs.604321
RefSeq NM_032888 XM_006717310
HUGO
OMIM
CCDS CCDS6802
HPRD 09767
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca