Version 5.4
Homo sapiens Gene: RAB31
Summary
InnateDB Gene IDBG-822.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB31
Gene Name RAB31, member RAS oncogene family
Synonyms Rab22B
Species Homo sapiens
Ensembl Gene ENSG00000168461
Encoded Proteins
IDBP-726275
IDBP-726147
IDBP-725580
IDBP-727711
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:9708165-9862551
Strand Forward strand
Band p11.22
Transcripts
ENST00000435762
ENST00000577284
ENST00000580795
ENST00000578921 ENSP00000461945
ENST00000578737
ENST00000581109 ENSP00000464046
ENST00000583137 ENSP00000462561
ENST00000577796
ENST00000580361
ENST00000577371
ENST00000583921
ENST00000578734 ENSP00000462164
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0031623 receptor internalization
GO:0032869 cellular response to insulin stimulus
GO:0043001 Golgi to plasma membrane protein transport
GO:0045055 regulated secretory pathway
GO:0048193 Golgi vesicle transport
GO:0090382 phagosome maturation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005802 trans-Golgi network
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0032588 trans-Golgi network membrane
GO:0045335 phagocytic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056515
View Gene Order
ENSBTAG00000046533
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.743265
RefSeq NM_006868
HUGO
OMIM
CCDS CCDS45826
HPRD 05751
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca