Version 5.4
Homo sapiens Gene: TRIP12
Summary
InnateDB Gene IDBG-82749.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIP12
Gene Name thyroid hormone receptor interactor 12
Synonyms TRIP-12; ULF
Species Homo sapiens
Ensembl Gene ENSG00000153827
Encoded Proteins
IDBP-78544
thyroid hormone receptor interactor 12
IDBP-82751
thyroid hormone receptor interactor 12
IDBP-82753
thyroid hormone receptor interactor 12
IDBP-82755
thyroid hormone receptor interactor 12
IDBP-292944
thyroid hormone receptor interactor 12
IDBP-389197
thyroid hormone receptor interactor 12
IDBP-389198
thyroid hormone receptor interactor 12
IDBP-389199
thyroid hormone receptor interactor 12
IDBP-389200
thyroid hormone receptor interactor 12
IDBP-389201
thyroid hormone receptor interactor 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:229763838-229923239
Strand Reverse strand
Band q36.3
Transcripts
ENST00000343290 ENSP00000342442
ENST00000283943 ENSP00000283943
ENST00000389045 ENSP00000373697
ENST00000389044 ENSP00000373696
ENST00000409677 ENSP00000386388
ENST00000418123 ENSP00000408330
ENST00000453485 ENSP00000400967
ENST00000435716 ENSP00000409460
ENST00000428959 ENSP00000414385
ENST00000430954 ENSP00000389827
ENST00000459841
ENST00000470302
ENST00000495322
ENST00000461189
ENST00000487178
ENST00000479037
ENST00000477441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0009790 embryo development
GO:0016567 protein ubiquitination
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 negative regulation of double-strand break repair
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026219
View Gene Order
ENSBTAG00000021653
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591633
RefSeq NM_001284214 NM_001284215 NM_001284216 NM_004238 XM_005246954 XM_005246955 XM_005246956 XM_005246957 XM_005246958 XM_005246960 XM_005246961 XM_005246962 XM_006712852 XM_006712853
HUGO
OMIM
CCDS CCDS33391 CCDS63145 CCDS63146
HPRD 05144
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca