Version 5.4
Homo sapiens Gene: IL13RA2
Summary
InnateDB Gene IDBG-82958.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL13RA2
Gene Name interleukin 13 receptor, alpha 2
Synonyms CD213A2; CT19; IL-13R; IL13BP
Species Homo sapiens
Ensembl Gene ENSG00000123496
Encoded Proteins
IDBP-82960
interleukin 13 receptor, alpha 2
IDBP-82962
interleukin 13 receptor, alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:115003975-115019977
Strand Reverse strand
Band q23
Transcripts
ENST00000371936 ENSP00000361004
ENST00000243213 ENSP00000243213
ENST00000468224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031289
View Gene Order
ENSBTAG00000020022
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04630
Jak-STAT signaling pathway pathway
INOH
INOH website
JAK STAT pathway and regulation pathway
INOH website
IL-13 signaling pathway
PID NCI
il4_2pathway
IL4-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_000640
HUGO
OMIM
CCDS CCDS14565
HPRD 02132
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca