Version 5.4
Homo sapiens Gene: HJURP
Summary
InnateDB Gene IDBG-83882.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HJURP
Gene Name Holliday junction recognition protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000123485
Encoded Proteins
IDBP-389406
Holliday junction recognition protein
IDBP-389407
Holliday junction recognition protein
IDBP-389408
Holliday junction recognition protein
IDBP-389409
Holliday junction recognition protein
IDBP-389410
Holliday junction recognition protein
IDBP-389411
Holliday junction recognition protein
IDBP-389413
Holliday junction recognition protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:233833416-233854566
Strand Reverse strand
Band q37.1
Transcripts
ENST00000373395
ENST00000433484 ENSP00000395207
ENST00000411486 ENSP00000414109
ENST00000432087 ENSP00000407208
ENST00000441687 ENSP00000401944
ENST00000414924 ENSP00000393253
ENST00000454020 ENSP00000414051
ENST00000434039
ENST00000453122 ENSP00000403668
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042393 histone binding
GO:0042802 identical protein binding
Biological Process
GO:0006334 nucleosome assembly
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0034080 centromere-specific nucleosome assembly
GO:0043254 regulation of protein complex assembly
GO:0051101 regulation of DNA binding
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044783
View Gene Order
ENSBTAG00000024726
Not yet available
Pathways
NETPATH
REACTOME
REACT_22186
Deposition of new CENPA-containing nucleosomes at the centromere pathway
REACT_22172
Chromosome Maintenance pathway
REACT_22344
Nucleosome assembly pathway
REACT_115566
Cell Cycle pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8WCV1
UniProt Splice Variant
Entrez Gene 55355
UniGene Hs.532968
RefSeq NM_001282962 NM_001282963 NM_018410
HUGO HGNC:25444
OMIM 612667
CCDS CCDS33406 CCDS63166 CCDS63167
HPRD
IMGT
EMBL AC005538
GenPept
RNA Seq Atlas 55355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca