Homo sapiens Gene: CPSF3L
Summary
InnateDB Gene IDBG-85005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPSF3L
Gene Name cleavage and polyadenylation specific factor 3-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127054
Encoded Proteins
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
cleavage and polyadenylation specific factor 3-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:1311585-1324691
Strand Reverse strand
Band p36.33
Transcripts
ENST00000323275
ENST00000435064 ENSP00000413493
ENST00000421495 ENSP00000464436
ENST00000411962 ENSP00000400548
ENST00000458452 ENSP00000433930
ENST00000450926 ENSP00000392848
ENST00000419704 ENSP00000404886
ENST00000434694 ENSP00000411233
ENST00000430786 ENSP00000404012
ENST00000429572 ENSP00000481275
ENST00000470030
ENST00000497304
ENST00000462432
ENST00000478641
ENST00000485710
ENST00000461514
ENST00000467408
ENST00000488042
ENST00000498173
ENST00000496353
ENST00000493534
ENST00000490853
ENST00000498476 ENSP00000436824
ENST00000470679 ENSP00000434782
ENST00000532772 ENSP00000431214
ENST00000527098 ENSP00000431952
ENST00000525164
ENST00000528879 ENSP00000432777
ENST00000525769
ENST00000531377 ENSP00000433264
ENST00000527383 ENSP00000431425
ENST00000531292
ENST00000531020
ENST00000533916
ENST00000526797 ENSP00000435418
ENST00000526332 ENSP00000434790
ENST00000527719 ENSP00000436743
ENST00000530031 ENSP00000432009
ENST00000526113
ENST00000526904
ENST00000525603
ENST00000534345 ENSP00000435772
ENST00000532952
ENST00000531019 ENSP00000433733
ENST00000525285 ENSP00000436396
ENST00000530233
ENST00000540437 ENSP00000445001
ENST00000545578 ENSP00000444672
ENST00000620829 ENSP00000481821
ENST00000618806 ENSP00000480957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0016180 snRNA processing
Cellular Component
GO:0005737 cytoplasm
GO:0032039 integrator complex
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL Q96HV7
UniProt Splice Variant
Entrez Gene 54973
UniGene
RefSeq NM_017871 NM_001256463 NM_001256456 NM_001256460 NM_001256462 XM_006710715 XM_005244763
HUGO HGNC:26052
OMIM 611354
CCDS CCDS21 CCDS57961 CCDS57960 CCDS57959 CCDS72678
HPRD
IMGT
EMBL BC008041 BC020199
GenPept AAH08041 AAH20199
RNA Seq Atlas 102465435 102723551 54973