Version 5.4
Homo sapiens Gene: ANGPTL2
Summary
InnateDB Gene IDBG-85645.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANGPTL2
Gene Name angiopoietin-like 2
Synonyms ARP2; HARP
Species Homo sapiens
Ensembl Gene ENSG00000136859
Encoded Proteins
IDBP-85647
angiopoietin-like 2
IDBP-85649
angiopoietin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:127087332-127122883
Strand Reverse strand
Band q33.3
Transcripts
ENST00000373425 ENSP00000362524
ENST00000373417 ENSP00000362516
ENST00000470194
ENST00000491991
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004105
View Gene Order
ENSBTAG00000011810
Not yet available
Cross-References
SwissProt
TrEMBL Q8NCH7
UniProt Splice Variant
Entrez Gene 23452
UniGene Hs.653262
RefSeq NM_012098
HUGO HGNC:490
OMIM 605001
CCDS CCDS6868
HPRD 05415
IMGT
EMBL AK074726 AL356862 CH471090
GenPept BAC11164 EAW87651
RNA Seq Atlas 23452

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca