Homo sapiens Gene: GLP1R
Summary
InnateDB Gene IDBG-86118.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLP1R
Gene Name glucagon-like peptide 1 receptor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112164
Encoded Proteins
glucagon-like peptide 1 receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:39048798-39087743
Strand Forward strand
Band p21.2
Transcripts
ENST00000373256 ENSP00000362353
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004967 glucagon receptor activity
Biological Process
GO:0006112 energy reserve metabolic process
GO:0006950 response to stress
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007611 learning or memory
GO:0008016 regulation of heart contraction
GO:0019933 cAMP-mediated signaling
GO:0044281 small molecule metabolic process
GO:0050796 regulation of insulin secretion
GO:0071377 cellular response to glucagon stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
G alpha (s) signalling events pathway
Integration of energy metabolism pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Glucagon-type ligand receptors pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
GPCR ligand binding pathway
Regulation of insulin secretion pathway
Metabolism pathway
Class B/2 (Secretin family receptors) pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P43220
TrEMBL
UniProt Splice Variant
Entrez Gene 2740
UniGene Hs.389103
RefSeq NM_002062 XM_006715065
HUGO HGNC:4324
OMIM 138032
CCDS CCDS4839
HPRD
IMGT
EMBL AB065685 AL035690 AY439112 BC112126 BC113493 L23503 U01104 U01156 U01157 U10037 U66062
GenPept AAA03614 AAA17021 AAA62471 AAA63787 AAB64013 AAC50050 AAI12127 AAI13494 AAR05444 BAC05908 CAB71177
RNA Seq Atlas 2740