Version 5.4
Homo sapiens Gene: STMN3
Summary
InnateDB Gene IDBG-86738.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STMN3
Gene Name stathmin-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197457
Encoded Proteins
IDBP-86740
stathmin-like 3
IDBP-583534
stathmin-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:63639705-63653427
Strand Reverse strand
Band q13.33
Transcripts
ENST00000370053 ENSP00000359070
ENST00000540534 ENSP00000439840
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015631 tubulin binding
GO:0019904 protein domain specific binding
Biological Process
GO:0007399 nervous system development
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0031122 cytoplasmic microtubule organization
GO:0031175 neuron projection development
GO:0032314 regulation of Rac GTPase activity
GO:0035021 negative regulation of Rac protein signal transduction
GO:0051493 regulation of cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030424 axon
GO:0030426 growth cone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027581
View Gene Order
ENSBTAG00000038974
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001276310 NM_015894
HUGO
OMIM
CCDS CCDS13529 CCDS63330
HPRD 16324
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca