Homo sapiens Gene: STMN3
Summary
InnateDB Gene IDBG-86738.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STMN3
Gene Name stathmin-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197457
Encoded Proteins
stathmin-like 3
stathmin-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:63639705-63653427
Strand Reverse strand
Band q13.33
Transcripts
ENST00000370053 ENSP00000359070
ENST00000540534 ENSP00000439840
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015631 tubulin binding
GO:0019904 protein domain specific binding
Biological Process
GO:0007399 nervous system development
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0031122 cytoplasmic microtubule organization
GO:0031175 neuron projection development
GO:0032314 regulation of Rac GTPase activity
GO:0035021 negative regulation of Rac protein signal transduction
GO:0051493 regulation of cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0030424 axon
GO:0030426 growth cone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL B7Z5G4
UniProt Splice Variant
Entrez Gene 50861
UniGene
RefSeq NM_001276310 NM_015894
HUGO HGNC:15926
OMIM 608362
CCDS CCDS63330 CCDS13529
HPRD 16324
IMGT
EMBL AK298903 AL353715
GenPept BAH12900
RNA Seq Atlas 50861