Version 5.4
Homo sapiens Gene: LZTS2
Summary
InnateDB Gene IDBG-86869.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LZTS2
Gene Name leucine zipper, putative tumor suppressor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000107816
Encoded Proteins
IDBP-86871
leucine zipper, putative tumor suppressor 2
IDBP-86873
leucine zipper, putative tumor suppressor 2
IDBP-384529
leucine zipper, putative tumor suppressor 2
IDBP-384531
leucine zipper, putative tumor suppressor 2
IDBP-384537
leucine zipper, putative tumor suppressor 2
IDBP-810425
leucine zipper, putative tumor suppressor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:100996618-101007836
Strand Forward strand
Band q24.31
Transcripts
ENST00000370223 ENSP00000359243
ENST00000370220 ENSP00000359240
ENST00000426584 ENSP00000407713
ENST00000429732 ENSP00000402042
ENST00000454422 ENSP00000416972
ENST00000489526
ENST00000481129 ENSP00000474819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000910 cytokinesis
GO:0001822 kidney development
GO:0007067 mitotic nuclear division
GO:0008285 negative regulation of cell proliferation
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0051013 microtubule severing
GO:0051168 nuclear export
GO:0051255 spindle midzone assembly
GO:0072001 renal system development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1900181 negative regulation of protein localization to nucleus
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0030496 midbody
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035342
View Gene Order
ENSBTAG00000003298
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.523221
RefSeq NM_032429 XM_005270223 XM_005270224
HUGO
OMIM
CCDS CCDS7507
HPRD 14341
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca