Homo sapiens Gene: KAZALD1
Summary
InnateDB Gene IDBG-86987.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KAZALD1
Gene Name Kazal-type serine peptidase inhibitor domain 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000107821
Encoded Proteins
Kazal-type serine peptidase inhibitor domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that this gene product may have a function in bone development and bone regeneration. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:101061841-101068131
Strand Forward strand
Band q24.31
Transcripts
ENST00000370200 ENSP00000359219
ENST00000477979
ENST00000470106
ENST00000477267
ENST00000465807
ENST00000608812
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
Biological Process
GO:0001503 ossification
GO:0001558 regulation of cell growth
GO:0007275 multicellular organismal development
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005576 extracellular region
GO:0005614 interstitial matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q96I82
TrEMBL
UniProt Splice Variant
Entrez Gene 81621
UniGene Hs.632079 Hs.733496
RefSeq NM_030929 XM_005270193 XM_005270194
HUGO HGNC:25460
OMIM 609208
CCDS CCDS7509
HPRD 13755
IMGT
EMBL AF333487 AK172862 AL133215 AY014271 AY359087 BC007758 CH471066
GenPept AAG50291 AAG50354 AAH07758 AAQ89445 BAD18818 CAI10937 CAI10938 EAW49782 EAW49783 EAW49784
RNA Seq Atlas 81621