Homo sapiens Gene: SLC25A25
Summary
InnateDB Gene IDBG-87248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A25
Gene Name solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148339
Encoded Proteins
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:128068201-128109245
Strand Forward strand
Band q34.11
Transcripts
ENST00000373069 ENSP00000362160
ENST00000373068 ENSP00000362159
ENST00000373066 ENSP00000362157
ENST00000373064 ENSP00000362155
ENST00000445012
ENST00000432073 ENSP00000410053
ENST00000472769 ENSP00000419685
ENST00000466983 ENSP00000418600
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0002021 response to dietary excess
GO:0014823 response to activity
GO:0032094 response to food
GO:0035264 multicellular organism growth
GO:0043010 camera-type eye development
GO:0045333 cellular respiration
GO:0046034 ATP metabolic process
GO:0060612 adipose tissue development
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q6KCM7
TrEMBL F8WEY9
UniProt Splice Variant
Entrez Gene 114789
UniGene Hs.5476
RefSeq NM_001006641 NM_001006642 NM_001265614 NM_052901 XM_005251688 XM_006716948 XM_006716949
HUGO HGNC:20663
OMIM 608745
CCDS CCDS35151 CCDS48031 CCDS59146 CCDS6890
HPRD
IMGT
EMBL AB067483 AJ619963 AJ619989 AJ619990 AJ619991 AJ619992 AK290705 AK290991 AL360268 AL590708 AY358515 BC005163 BC089448 BC103930 BC103931 BC103932 BC103933 CH471090
GenPept AAH05163 AAH89448 AAI03931 AAI03932 AAI03933 AAI03934 AAQ88879 BAB67789 BAF83394 BAF83680 CAF04060 CAF04495 CAF04496 CAF04497 CAF04498 CAH73133 CAH73134 CAH73135 CAH73136 CAI13826 CAI13827 CAI13836 CAI13838 EAW87739
RNA Seq Atlas 114789