Homo sapiens Gene: FHL1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-87389.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | FHL1 | ||||||||||||||||||
Gene Name | four and a half LIM domains 1 | ||||||||||||||||||
Synonyms | FHL-1; FHL1A; FHL1B; FLH1A; KYOT; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000022267 | ||||||||||||||||||
Encoded Proteins |
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome X:136147400-136211359 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q26.3 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH |
Notch pathway
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REACTOME | |||||||||||||||||||
KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | Q5JXH7 Q5JXH8 Q5JXH9 Q5JXI0 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 2273 | ||||||||||||||||||
UniGene | Hs.435369 Hs.619207 | ||||||||||||||||||
RefSeq | NM_001159699 NM_001159700 NM_001159701 NM_001159702 NM_001159703 NM_001159704 NM_001167819 NM_001449 XM_006724743 XM_006724744 XM_006724745 XM_006724746 XM_006724747 | ||||||||||||||||||
HUGO | HGNC:3702 | ||||||||||||||||||
OMIM | 300163 | ||||||||||||||||||
CCDS | CCDS14655 CCDS55505 CCDS55506 CCDS55507 CCDS76036 | ||||||||||||||||||
HPRD | 02157 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AL078638 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 2273 | ||||||||||||||||||