Version 5.4
| Homo sapiens Gene: FHL1 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-87389.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | FHL1 | ||||||||||||||||||
| Gene Name | four and a half LIM domains 1 | ||||||||||||||||||
| Synonyms | FHL-1; FHL1A; FHL1B; FLH1A; KYOT; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000022267 | ||||||||||||||||||
| Encoded Proteins |
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
four and a half LIM domains 1
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome X:136147400-136211359 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q26.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH |
Notch pathway
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| REACTOME | |||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | Q5JXH7 Q5JXH8 Q5JXH9 Q5JXI0 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 2273 | ||||||||||||||||||
| UniGene | Hs.435369 Hs.619207 | ||||||||||||||||||
| RefSeq | NM_001159699 NM_001159700 NM_001159701 NM_001159702 NM_001159703 NM_001159704 NM_001167819 NM_001449 XM_006724743 XM_006724744 XM_006724745 XM_006724746 XM_006724747 | ||||||||||||||||||
| HUGO | HGNC:3702 | ||||||||||||||||||
| OMIM | 300163 | ||||||||||||||||||
| CCDS | CCDS14655 CCDS55505 CCDS55506 CCDS55507 CCDS76036 | ||||||||||||||||||
| HPRD | 02157 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AL078638 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 2273 | ||||||||||||||||||