Homo sapiens Gene: ARL4A
Summary
InnateDB Gene IDBG-8759.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARL4A
Gene Name ADP-ribosylation factor-like 4A
Synonyms ARL4;
Species Homo sapiens
Ensembl Gene ENSG00000122644
Encoded Proteins
ADP-ribosylation factor-like 4A
ADP-ribosylation factor-like 4A
ADP-ribosylation factor-like 4A
ADP-ribosylation factor-like 4A
ADP-ribosylation factor-like 4A
ADP-ribosylation factor-like 4A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:12686856-12690934
Strand Forward strand
Band p21.3
Transcripts
ENST00000356797 ENSP00000349250
ENST00000396664 ENSP00000379899
ENST00000396663 ENSP00000379898
ENST00000396662 ENSP00000379897
ENST00000404894 ENSP00000385236
ENST00000439721 ENSP00000397651
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.245540 Hs.603315 Hs.741524
RefSeq NM_001037164 NM_001195396 NM_005738 NM_212460
HUGO
OMIM
CCDS CCDS5359
HPRD 11987
IMGT
EMBL
GenPept
RNA Seq Atlas