Version 5.4
Homo sapiens Gene: ELOVL3
Summary
InnateDB Gene IDBG-87837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELOVL3
Gene Name ELOVL fatty acid elongase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000119915
Encoded Proteins
IDBP-87839
ELOVL fatty acid elongase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ELOVL3 plays a role in fatty acid chain elongation and formation of neutral lipids required for skin barrier function (Westerberg et al., 2004 [PubMed 14581464]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:102226328-102229589
Strand Forward strand
Band q24.32
Transcripts
ENST00000370005 ENSP00000359022
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016740 transferase activity
Biological Process
GO:0019367 fatty acid elongation, saturated fatty acid
GO:0019432 triglyceride biosynthetic process
GO:0034625 fatty acid elongation, monounsaturated fatty acid
GO:0034626 fatty acid elongation, polyunsaturated fatty acid
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0042761 very long-chain fatty acid biosynthetic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038754
View Gene Order
ENSBTAG00000015700
Not yet available
Pathways
NETPATH
REACTOME
REACT_380
Synthesis of very long-chain fatty acyl-CoAs pathway
REACT_1319
Fatty Acyl-CoA Biosynthesis pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_118789
REV-ERBA represses gene expression pathway
REACT_24941
Circadian Clock pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt Q9HB03
TrEMBL
UniProt Splice Variant
Entrez Gene 83401
UniGene Hs.302130
RefSeq NM_152310
HUGO HGNC:18047
OMIM 611815
CCDS CCDS7531
HPRD
IMGT
EMBL AF292387 AL160011 BC034344 CH471066
GenPept AAG17875 AAH34344 CAH71623 EAW49711
RNA Seq Atlas 83401

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca