InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ELOVL3

Summary

InnateDB Protein

IDBP-87839.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELOVL3

Protein Name

ELOVL fatty acid elongase 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000359022

InnateDB Gene

IDBG-87837 (ELOVL3)

Protein Structure

UniProt Annotation

Function

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. {ECO:0000269PubMed:20937905}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000269PubMed:20937905}; Multi-pass membrane protein {ECO:0000269PubMed:20937905}.

Disease Associations

Tissue Specificity

Testis. {ECO:0000269PubMed:20937905}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016740	transferase activity

Biological Process

GO:0019367	fatty acid elongation, saturated fatty acid
GO:0019432	triglyceride biosynthetic process
GO:0034625	fatty acid elongation, monounsaturated fatty acid
GO:0034626	fatty acid elongation, polyunsaturated fatty acid
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
GO:0042761	very long-chain fatty acid biosynthetic process
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process