Homo sapiens Gene: CA6
Summary
InnateDB Gene IDBG-88412.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA6
Gene Name carbonic anhydrase VI
Synonyms CA-VI; GUSTIN;
Species Homo sapiens
Ensembl Gene ENSG00000131686
Encoded Proteins
carbonic anhydrase VI
carbonic anhydrase VI
carbonic anhydrase VI
carbonic anhydrase VI
carbonic anhydrase VI
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:8945867-8975092
Strand Forward strand
Band p36.23
Transcripts
ENST00000377443 ENSP00000366662
ENST00000377442 ENSP00000366661
ENST00000377436 ENSP00000366654
ENST00000476083
ENST00000480186 ENSP00000435280
ENST00000549778 ENSP00000447108
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006730 one-carbon metabolic process
GO:0015701 bicarbonate transport
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Reversible hydration of carbon dioxide pathway
Metabolism pathway
KEGG
Nitrogen metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P23280
TrEMBL
UniProt Splice Variant
Entrez Gene 765
UniGene
RefSeq NM_001270501 NM_001215 NM_001270500
HUGO HGNC:1380
OMIM 114780
CCDS CCDS57971 CCDS30578 CCDS57970
HPRD 00264
IMGT
EMBL AB102863 AB103091 AF128411 AF128412 AF128413 AF128414 AF128415 AF128416 AF128417 AF128418 AL139415 M57892
GenPept AAA51892 AAF22565 BAD89397 BAD89434 CAC42429
RNA Seq Atlas 765