Version 5.4
| Homo sapiens Gene: CRISP1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-90311.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CRISP1 | ||||||||
| Gene Name | cysteine-rich secretory protein 1 | ||||||||
| Synonyms | AEGL1; ARP; CRISP-1; HSCRISP1D; HSCRISP1G; HUMARP | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000124812 | ||||||||
| Encoded Proteins |
cysteine-rich secretory protein 1
cysteine-rich secretory protein 1
cysteine-rich secretory protein 1
cysteine-rich secretory protein 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:49834257-49877096 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | p12.3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | P54107 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 167 | ||||||||
| UniGene | Hs.109620 | ||||||||
| RefSeq | NM_001205220 NM_001131 NM_170609 XM_006715003 | ||||||||
| HUGO | HGNC:304 | ||||||||
| OMIM | 601193 | ||||||||
| CCDS | CCDS4931 CCDS4932 | ||||||||
| HPRD | 03118 | ||||||||
| IMGT | |||||||||
| EMBL | AB451334 AB451479 AL359458 D38451 S80310 X95237 X95238 | ||||||||
| GenPept | AAB35899 BAA07483 BAG70148 BAG70293 CAA64524 CAA64525 CAC34980 | ||||||||
| RNA Seq Atlas | 167 | ||||||||