Version 5.4
Homo sapiens Gene: GTF3C4
Summary
InnateDB Gene IDBG-90380.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF3C4
Gene Name general transcription factor IIIC, polypeptide 4, 90kDa
Synonyms KAT12; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA
Species Homo sapiens
Ensembl Gene ENSG00000125484
Encoded Proteins
IDBP-90382
general transcription factor IIIC, polypeptide 4, 90kDa
IDBP-591453
general transcription factor IIIC, polypeptide 4, 90kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:132670035-132694955
Strand Forward strand
Band q34.13
Transcripts
ENST00000372146 ENSP00000361219
ENST00000483873 ENSP00000431378
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
Experimentally validated
Total 59 [view]
Protein-Protein 56 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0010467 gene expression
GO:0016573 histone acetylation
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0042797 tRNA transcription from RNA polymerase III promoter
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0000127 transcription factor TFIIIC complex
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035666
View Gene Order
ENSBTAG00000004091
Not yet available
Pathways
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F2Z356
UniProt Splice Variant
Entrez Gene 9329
UniGene Hs.22302 Hs.656646 Hs.734179
RefSeq NM_012204
HUGO HGNC:4667
OMIM 604892
CCDS CCDS6953
HPRD 11998
IMGT
EMBL AL160165
GenPept
RNA Seq Atlas 9329

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca