Version 5.4
Homo sapiens Gene: PRLHR
Summary
InnateDB Gene IDBG-90930.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRLHR
Gene Name prolactin releasing hormone receptor
Synonyms GPR10; GR3; PrRPR
Species Homo sapiens
Ensembl Gene ENSG00000119973
Encoded Proteins
IDBP-90934
prolactin releasing hormone receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:118589989-118595699
Strand Reverse strand
Band q26.11
Transcripts
ENST00000239032 ENSP00000239032
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004983 neuropeptide Y receptor activity
GO:0005515 protein binding
GO:0008188 neuropeptide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007565 female pregnancy
GO:0007631 feeding behavior
GO:0042445 hormone metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045052
View Gene Order
ENSBTAG00000047842
Not yet available
Pathways
NETPATH
REACTOME
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt P49683
TrEMBL
UniProt Splice Variant
Entrez Gene 2834
UniGene Hs.248119
RefSeq NM_004248
HUGO HGNC:4464
OMIM 600895
CCDS CCDS7606
HPRD
IMGT
EMBL AB015745 AB048946 AL356865 BC095539 BC101490 BC101492 U32672
GenPept AAC50504 AAH95539 AAI01491 AAI01493 BAA31159 BAB83030 CAH73066
RNA Seq Atlas 2834

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca