Version 5.4
Homo sapiens Gene: ARHGEF10L
Summary
InnateDB Gene IDBG-91886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF10L
Gene Name Rho guanine nucleotide exchange factor (GEF) 10-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074964
Encoded Proteins
IDBP-91888
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-91892
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-91894
Rho guanine nucleotide exchange factor (GEF) 10-like
IDBP-91896
Rho guanine nucleotide exchange factor (GEF) 10-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:17539835-17697874
Strand Forward strand
Band p36.13
Transcripts
ENST00000361221 ENSP00000355060
ENST00000375415 ENSP00000364564
ENST00000375408 ENSP00000364557
ENST00000167825 ENSP00000167825
ENST00000482892
ENST00000469726
ENST00000482359
ENST00000466782
ENST00000495593
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000040964
View Gene Order
Ortholuge
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
ENSBTAG00000000684
Not yet available
Ortholuge
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001011722 NM_018125 XM_005245923 XM_005245924 XM_005245925 XM_005245926 XM_005245927 XM_005245929 XM_006710727 XM_006710728 XM_006710729 XM_006710730 XM_006710731 XM_006710732 XM_006710733 XM_006710734
HUGO
OMIM
CCDS CCDS182 CCDS30617
HPRD 07679
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca