Homo sapiens Gene: ARHGEF10L
Summary
InnateDB Gene IDBG-91886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF10L
Gene Name Rho guanine nucleotide exchange factor (GEF) 10-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074964
Encoded Proteins
Rho guanine nucleotide exchange factor (GEF) 10-like
Rho guanine nucleotide exchange factor (GEF) 10-like
Rho guanine nucleotide exchange factor (GEF) 10-like
Rho guanine nucleotide exchange factor (GEF) 10-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:17539835-17697874
Strand Forward strand
Band p36.13
Transcripts
ENST00000361221 ENSP00000355060
ENST00000375415 ENSP00000364564
ENST00000375408 ENSP00000364557
ENST00000167825 ENSP00000167825
ENST00000482892
ENST00000469726
ENST00000482359
ENST00000466782
ENST00000495593
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Regulation of RhoA activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001011722 NM_018125 XM_005245923 XM_005245924 XM_005245925 XM_005245926 XM_005245927 XM_005245929 XM_006710727 XM_006710728 XM_006710729 XM_006710730 XM_006710731 XM_006710732 XM_006710733 XM_006710734
HUGO
OMIM
CCDS CCDS182 CCDS30617
HPRD 07679
IMGT
EMBL
GenPept
RNA Seq Atlas